Single-oral-dose azithromycin prophylaxis against experimental streptococcal or staphylococcal aortic valve endocarditis.

نویسندگان

  • A Tsitsika
  • A Pefanis
  • G S Perdikaris
  • I Donta
  • P Karayiannakos
  • H Giamarellou
چکیده

Azithromycin and ampicillin protected 94 and 72% of animals challenged with Streptococcus oralis, respectively (P = 0.177), while azithromycin and vancomycin protected 59 and 94% of the methicillin-resistant Staphylococcus aureus (MRSA)-challenged animals, respectively (P = 0.018). Azithromycin is effective in preventing experimental streptococcal endocarditis, but against MRSA it is less effective than vancomycin.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 44 6  شماره 

صفحات  -

تاریخ انتشار 2000